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Dr. Caroline Debbasch Caroline Debbasch, a PhD graduate of l'Universite Paris-V, is a Pharmacist who specializes in Ophthalmo-Toxicology at L'Oreal, Applied Research and Development, France. Dr. Debbasch began her research in XV-XX National Ophthalmological Hospital and she worked first on hepatocytes. Very quickly and thanks to the ophthalmological team she was working with, she developed a true passion for the eye and more specifically for the ocular surface. Since then, Dr. Debbasch has worked on the ocular surface and specifically on preservative toxicity both in vitro (by using human conjunctival cell lines) and ex vivo (by using impression cytology). Her PhD work particularly focused on anti-glaucomatous, tear substitutes, anti-allergic and so on to evaluate eye toxicity. More specifically, Dr. Debbasch investigated cytotoxicity and inflammatory mechanisms, inflammation being the key mechanism behind all ocular surface disorders. While doing her PhD, Dr. Debbasch joined ARVO in 1999 and the Tear Film & Ocular Surface Society in 2000. Dr. Debbasch's research gave her the opportunity to work for the prestigious cosmetic company, L'Oreal, Applied Research and Development. She took a position in the International Safety Evaluation Department, where she was first responsible for safety evaluation of products from applied research laboratories. Now in charge of skin care products safety evaluation, Dr. Debbasch continues her ophthalmic basic and clinical research activities. Her division in L'Oreal focuses on three main areas of ocular surface disorders, including irritation, inflammation and allergy, which are the most relevant ocular research fields for the company. Moreover, Dr. Debbasch works on various topics such as cytokines and inflammation, raw materials and ocular tolerance, as well as worldwide harmonisation and development of new clinical ophthalmic protocols. For L'Oreal, Dr. DebbaschÕs contribution is of outmost importance for helping the company to develop safe cosmetic products to be used in the periocular area. A strong knowledge of the ocular surface, particularly of the tear film and its modifications during life, is extremely valuable for L'Oreal. Furthermore, this knowlege is very critical in order to develop cosmetic formulas specifically designed for contact lens wearers and/or consumers with sensitive eyes or ocular surface disorders (blepharitis, rosacea, Meibomian gland dysfunctionÉ).
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